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Parabolic dependence of drug action upon lipophilic character as revealed by a study of hypnotics Corwin Hansch, A. Ruth Steward, Susan M. Anderson, and Donald L. Bentley pp 1 - 11; DOI: 10.1021/jm00307a001 |
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Stereochemical studies on medicinal agents. V. Synthesis, configuration, and pharmacological activity of pipradrol enantiomers Philip S. Portoghese, T. L. Pazdernik, William L. Kuhn, Gilbert Hite, and Abbas Shafi'ee pp 12 - 15; DOI: 10.1021/jm00307a002 |
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Enzyme inhibitors. XIX. Synthesis of some 1-hydroxy-2-hydroxymethyl-4-(6)substituted-9-purinyl)cyclohexanes as nucleoside analogs Howard J. Schaeffer and Robert Vince pp 15 - 20; DOI: 10.1021/jm00307a003 |
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Enzyme inhibitors. XX. The hydrophobic and hydroxyl-binding regions of adenosine deaminase. 9-(2-m-Bromo-acetamidophenethyl)adenine, a new irreversible inhibitor of adenosine deaminase Howard J. Schaeffer and Roland Norman Johnson pp 21 - 26; DOI: 10.1021/jm00307a004 |
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Irreversible enzyme inhibitors. CIX. Candidate irreversible inhibitors of dihydrofolic reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine. 3 Bernard Randall Baker and Gerhardus J. Lourens pp 26 - 33; DOI: 10.1021/jm00307a005 |
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Irreversible enzyme inhibitors. CX. Candidate irreversible inhibitors of dihydrofolic reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine. 4 Bernard Randall Baker and Gerhardus J. Lourens pp 34 - 37; DOI: 10.1021/jm00307a006 |
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Irreversible enzyme inhibitors. CXII. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine substituted with a terminal sulfonyl fluoride. 2 Bernard Randall Baker and Gerhardus J. Lourens pp 38 - 41; DOI: 10.1021/jm00307a007 |
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Lipid-Soluble derivatives of 6-mercaptopurine Carroll Temple, Conrad L. Kussner, and John A. Montgomery pp 41 - 44; DOI: 10.1021/jm00307a008 |
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Derivatives and analogs of 6-mercaptopurine ribonucleotide H. Jeanette Thomas and John A. Montgomery pp 44 - 48; DOI: 10.1021/jm00307a009 |
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Analogs of 6-methyl-9.beta.-D-ribofuranosylpurine John A. Montgomery and Kathleen Hewson pp 48 - 52; DOI: 10.1021/jm00307a010 |
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Nucleosides. XLV. 1-.alpha.-L-Aldopentofuranosylpyrimidines Naotaka Yamaoka, Brian A. Otter, and Jack J. Fox pp 55 - 59; DOI: 10.1021/jm00307a011 |
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DL-Willardiine mustard Abelardo P. Martinez, William Wei Lee, and Leon Goodman pp 60 - 62; DOI: 10.1021/jm00307a012 |
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Anticancer activity of P,P-bix(2-methyl-1-aziridinyl)-N-2-pyrimidinylphosphinic amide (methylphosphazine) and related compounds C. Wayne Noell and Chia-Chung Cheng pp 63 - 66; DOI: 10.1021/jm00307a013 |
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Antiprotozoans. Synthesis and biological activity of some styrylimidazole derivatives Pier N. Giraldi, V. Mariotti, and Ivo De Carneri pp 66 - 70; DOI: 10.1021/jm00307a014 |
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Penicillins and cephalosporins from isothiazolylacetic acids Rintje Raap and Ronald G. Micetich pp 70 - 73; DOI: 10.1021/jm00307a015 |
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Potential antiviral agents. Carbobenzoxy di- and tripeptides active against measles and herpes viruses Ernest D. Nicolaides, Horace A. De Wald, Roger D. Westland, Marilyn Lipnik, and Jeanette Posler pp 74 - 79; DOI: 10.1021/jm00307a016 |
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Nitrofuryl heterocycles. VII. 4-Amino-6-(5-nitro-2-furyl)-1H-pyrazolo[3,4-d]pyrimidines Homer A. Burch pp 79 - 83; DOI: 10.1021/jm00307a017 |
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1-Alkyl-1-(2-mercaptoethyl)quanidines and the corresponding thioureas, disulfides, and thiosulfates and thiosulfates and antibacterial agents Roger D. Westland, Eva R. Karger, Billie Green, and John R. Dice pp 84 - 86; DOI: 10.1021/jm00307a018 |
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Chemical and pharmacological investigations of some .omega.-substituted alkylamino-3-aminopyridines Padam C. Jain, V. Kapoor, Nitya Anand, Gyanendra K. Patnaik, Allauddin Ahmad, and Man M. Vohra pp 87 - 92; DOI: 10.1021/jm00307a019 |
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Silicon-containing barbiturates Igal Belsky, David Gertner, and Albert Zilkha pp 92 - 94; DOI: 10.1021/jm00307a020 |
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N-Substituted cyclopropylamines as monoamine oxidase inhibitors. Structure-activity relations. Dopa potentiation in mice and in vitro inhibition of kynuramine oxidation Jack Mills, Richard W. Kattau, Irwin H. Slater, and Ray W. Fuller pp 95 - 97; DOI: 10.1021/jm00307a021 |
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Synthesis and pharmacological properties of N-derivatives of 5,6-dihydro-7H,12H-dibenz[c,f]azocine, a new tricyclic system Silvano Casadio, Gianfranco Pala, Elda Crescenzi, Ernesta Marazzi-Uberti, Germano Coppi, and Carla Turba pp 97 - 100; DOI: 10.1021/jm00307a022 |
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Azepinoindoles. I. Hexahydroazepino[4,5-b]indoles Jackson B. Hester, Andrew H. Tang, Hugh H. Keasling, and William Veldkamp pp 101 - 106; DOI: 10.1021/jm00307a023 |
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Bisquaternary ammonium indolines and perhydroindoles in ganglionic blockade Mathias P. Mertes, Subhash A. Nerurkar, and Edward J. Walaszek pp 106 - 111; DOI: 10.1021/jm00307a024 |
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Preparation and antiinflammatory properties of some 5-(2-anilinophenyl)tetrazoles Peter F. Juby, T. W. Hudyma, and Morton Brown pp 111 - 117; DOI: 10.1021/jm00307a025 |
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Steroids. CCCX. Structure-activity relation of some steroidal hypnotic agents Laszlo Gyermek, Jose Iriarte, and Pierre Crabbe pp 117 - 125; DOI: 10.1021/jm00307a026 |
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The synthesis and biological activity of substituted 2,6-diaminopyridines Diether G. Markees, Virginia C. Dewey, and George W. Kidder pp 126 - 129; DOI: 10.1021/jm00307a027 |
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Antihypertensive 2-amino-4(3H)-quinazolinones Hans J. Hess, Timothy H. Cronin, and Alexander Scriabine pp 130 - 136; DOI: 10.1021/jm00307a028 |
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Some new 3-amino-2H-1,2,4-benzothiadiazine 1,1-dioxides Timothy H. Cronin and Hans-Juergen Hess pp 136 - 138; DOI: 10.1021/jm00307a029 |
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Fluorinated analogs of leucine, methionine, and valine Joseph Lazar and William A. Sheppard pp 138 - 140; DOI: 10.1021/jm00307a030 |
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Iodinated phenylalanines. Tests for selective localization in pancreas and preparation of 3,4,5-triiodophenylalanine Virginia B. Schatz, Barbara C. O'Brien, and William R. Sandusky pp 140 - 142; DOI: 10.1021/jm00307a031 |
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N2-Hydroxyasparagine Elvira A. Falco and George Bosworth Brown pp 142 - 143; DOI: 10.1021/jm00307a032 |
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Some 3-methyl-2-butenylaminopurines and -pyrimidines Arthur Myles and Jack J. Fox pp 143 - 144; DOI: 10.1021/jm00307a033 |
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Nucleosides. XLVII. Syntheses of some N4-substituted derivatives of 1-.beta.-D-arabinofuranosylcytosine and -5-fluorocytosine Iris Wempen, Naishun Miller, Elvira A. Falco, and Jack J. Fox pp 144 - 148; DOI: 10.1021/jm00307a034 |
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Nucleosides. XLVIII. Synthesis of 1-(5-deoxy-.beta.-D-arabinosyl)cytosine and related compounds Elvira A. Falco and Jack J. Fox pp 148 - 151; DOI: 10.1021/jm00307a035 |
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Branched-chain sugar nucleosides. II. 5',5'-Di-C-methyladenosine Ruth F. Nutt and Edward Walton pp 151 - 153; DOI: 10.1021/jm00307a036 |
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Potential anticancer agents. I. Synthesis of some nitrogen mustard containing benzylidenehydrazides M. G. Dhapalapur, S. S. Sabnis, and C. V. Deliwala pp 154 - 156; DOI: 10.1021/jm00307a037 |
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New salts of lucanthone as potential anticancer agents Benjamin Prescott pp 156 - 158; DOI: 10.1021/jm00307a038 |
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Steroids. XXX. Indolocholestanes and indolandrostanes Norman J. Doorenbos and Mu Tsu Wu pp 158 - 159; DOI: 10.1021/jm00307a039 |
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Penicillins from 3- and 5-phenylisothiazole-4-carboxylic acids and alkoxy derivatives R. G. Micetich and R. Raap pp 159 - 160; DOI: 10.1021/jm00307a040 |
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Quinoline antibacterial agents. Oxolinic acid and related compounds Daniel Kaminsky and Robert I. Meltzer pp 160 - 163; DOI: 10.1021/jm00307a041 |
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Some new p-(chlorophenoxy)carbanilides and their bacteriostatic activities D. Cobern and A. P. Rhodes pp 163 - 164; DOI: 10.1021/jm00307a042 |
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Synthesis and antimalarial evaluation of some 1,7-naphthridines and 2,9-diazaanthracenes Ping-Lu Chien and C. C. Cheng pp 164 - 167; DOI: 10.1021/jm00307a043 |
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1-Substitution in 2-methyl-4(5)-nitroimidazole. I. Synthesis of compounds with potential antitrichomonal activity F. Kajfez, V. Sunjic, D. Kolbah, T. Fajdiga, and M. Oklobdzija pp 167 - 170; DOI: 10.1021/jm00307a044 |
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Snthesis and herbicidal activity of 1,1-dimethyl- and 2-methyl-4-phenylsemicarbazides Merrill Wilcox pp 171 - 172; DOI: 10.1021/jm00307a045 |
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5-Aryl-1,5-dihydro-2H-1,4-benzodiazepin-2-ones Stanley C. Bell, Ronald J. McCaully, and Scott J. Childress pp 172 - 174; DOI: 10.1021/jm00307a046 |
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Substituent effects on ester carbonyl absorption and chemoreceptor responses initiated by tropanyl phenylacetates Seymour L. Friess and F. J. Fash pp 175 - 176; DOI: 10.1021/jm00307a047 |
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Methoxy derivatives of 5,5-diphenylhydantoin and 5-phenyl-5-benzylhydantoin Armando Novelli and Alberto M. De Santis pp 176 - 178; DOI: 10.1021/jm00307a048 |
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Synthesis of 3,5-bishydroxymethyl-6-methyl-2(1H)-pyridone, an isomer of pyridoxine Brian Jaques and John W. Hubbard pp 178 - 178; DOI: 10.1021/jm00307a049 |
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Benzo[b]thiophene derivatives. XI. 3-Aminomethyl-5-hydroxybenzo[b]thiophenes E. Campaigne and T. R. Bosin pp 178 - 180; DOI: 10.1021/jm00307a050 |
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Pyridoxine chemistry. XVII. Adamantoyl esters of pyridoxol W. Korytnyk and G. Fricke pp 180 - 181; DOI: 10.1021/jm00307a051 |
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Isoquinolines as cholinesterase inhibitors. I Ian W. Mathison pp 181 - 183; DOI: 10.1021/jm00307a052 |
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Diimides of cyclobutane-1,1-dicarboxylic acid Karimullah A. Zirvi and Charles H. Jarboe pp 183 - 183; DOI: 10.1021/jm00307a053 |
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Imidothiazoles Leonard M. Rice, Kenneth R. Scott, and Charles H. Grogan pp 183 - 185; DOI: 10.1021/jm00307a054 |
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Some hydrogenated dibenz[e,g]isoindoline derivatives Leonard M. Rice and Charles H. Grogan pp 185 - 186; DOI: 10.1021/jm00307a055 |
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Ethyl homologs of 2,4,5-trimethoxyphenylisopropylamine Alexander T. Shulgin pp 186 - 187; DOI: 10.1021/jm00307a056 |
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Probable conformations of some reversed esters of meperidine as solutes in water. Conformational factors in 4-phenylpiperidine analgetics Alan F. Casy pp 188 - 191; DOI: 10.1021/jm00307a057 |
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Effects of certain arylhydroxamic acids on deoxy-ribonucleic acid synthesis by Ehrlich ascites tumor cells in vitro Glen R. Gale and John B. Hynes pp 191 - 194; DOI: 10.1021/jm00307a058 |
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Microbiological transformation of steroids. II. Synthesis of 2.alpha.-methyl-19-nortestololactone Ronald D. Garrett and Judith T. McCurdy pp 194 - 195; DOI: 10.1021/jm00307a059 |
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Application of 1,3-di(4-piperidyl)propane in the Mannich reaction. Synthesis of .beta.-amino ketones Rajendra S. Varma and W. Lewis Nobles pp 195 - 195; DOI: 10.1021/jm00307a060 |
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Sulfonamides of hydroxylamine derivatives James H. Cooley, Bhupendra N. Misra, James R. Throckmorton, and William D. Bills pp 196 - 196; DOI: 10.1021/jm00307a061 |
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N4-Substituted N1-tolysulfonylpiperazines J. R. Shroff pp 196 - 197; DOI: 10.1021/jm00307a062 |
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The Synthesis and Properties of 2,6-Dihydroxylaminopurine and Its 9-β-D-Ribofuranosyl Derivative A. Giner-Sorolla, C. Nanos, J.H. Burchenal, M. Dollinger, and A. Bendich pp 52 - 54; DOI: 10.1021/jm00307a600 |
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Book Review: Ethnopharmacologic Search for Psychoactive Drugs Alfred Burger pp 198 - 198; DOI: 10.1021/jm00307a901 |
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Application of regression analyses to antitumor activities of various acetylenic carbamates William P. Purcell and John M. Clayton pp 199 - 203; DOI: 10.1021/jm00308a001 |
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A proton magnetic resonance study of N1-substituent effects on sulfanilamides Arthur Cammarata and Richard C. Allen pp 204 - 207; DOI: 10.1021/jm00308a002 |
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Researches in the indole series. XX. Quantum mechanical calculations and charge-transfer complexes of substituted indoles Philippe Millie, Jean P. Malrieu, Jean Benaim, J. Y. Lallemand, and Marc Julia pp 207 - 211; DOI: 10.1021/jm00308a003 |
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Charge-transfer complexes in medicinal chemistry. I. Correlations with the psychotropic activity of piperidinol esters and related compounds Thomas Nogrady and Aldo A. Algieri pp 212 - 213; DOI: 10.1021/jm00308a004 |
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Dipole moments and pharmacological activity of cyclic ureas, cyclic thioureas, and the N,N'-dimethylated compounds Eric J. C. Lien and Warren D. Kumler pp 214 - 219; DOI: 10.1021/jm00308a005 |
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Stereochemical studies on medicinal agents. VI. Bicyclic bases. Synthesis and pharmacology of epimeric bridged analogs of meperidine, 2-methyl-5-carbethoxy-2-azabicyclo[2.2.1]heptanes Philip S. Portoghese, Adel A. Mikhail, and Harvey J. Kupferberg pp 219 - 225; DOI: 10.1021/jm00308a006 |
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Experimentally induced phenylketonuria. II. Potential inhibitors of phenylalanine hydroxylase Joseph I. DeGraw, Michael Cory, Wilfred A. Skinner, Myna C. Theisen, and Chozo Mitoma pp 225 - 227; DOI: 10.1021/jm00308a007 |
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In vitro activity of sulfonamides against red cell carbonic anhydrases. Effect of ionic and substrate variation on the hydration reaction Thomas H. Maren and Christine E. Wiley pp 228 - 232; DOI: 10.1021/jm00308a008 |
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Irreversible enzyme inhibitors. CXIII. Proteolytic enzymes. 3. Active-site-directed irreversible inhibitors of .alpha.-chymotrypsin derived from phenoxyacetamides with an N-fluoro-sulfonylphenyl substituent Bernard Randall Baker and Jeffrey A. Hurlbut pp 233 - 241; DOI: 10.1021/jm00308a009 |
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Irreversible enzyme inhibitors. CXIV. Proteolytic enzymes. 4. Additional active-site-directed irreversible inhibitors of .alpha.-chymotrypsin derived from phenoxyacetamides bearing a terminal sulfonyl fluoride Bernard Randall Baker and Jeffrey A. Hurlbut pp 241 - 245; DOI: 10.1021/jm00308a010 |
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Irreversible enzyme inhibitors. CXV. Proteolytic enzymes. 5. Active-site-directed irreversible inhibitors of trypsin derived from p-(phenoxyalkoxy)benzamidines with a terminal sulfonyl fluoride Bernard Randall Baker and Edward H. Erickson pp 245 - 249; DOI: 10.1021/jm00308a011 |
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Demethylation studies. V. The in vivo and in vitro N-demethylation of N,N-dimethyl-3,5,7-trimethyladamantane-1-carboxamide H. R. Sullivan, R. E. Billings, and R. E. McMahon pp 250 - 254; DOI: 10.1021/jm00308a012 |
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Preparation of vinblastine-4-acetyl-t and its distribution in the blood of rats H. F. Greenius, R. W. McIntyre, and Charles T. Beer pp 254 - 257; DOI: 10.1021/jm00308a013 |
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Synthesis of .alpha.-N-methylated histidines Vernon N. Reinhold, Yoshinori Ishikawa, and Donald B. Melville pp 258 - 260; DOI: 10.1021/jm00308a014 |
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.alpha.-Hydrazino analog of histidine Meyer Sletzinger, Raymond A. Firestone, Donald F. Reinhold, Clarence S. Rooney, and William H. Nicholson pp 261 - 263; DOI: 10.1021/jm00308a015 |
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Syntheses and biological activities of some cycloalkenealanines Thomas Hugh Porter, Robert M. Gipson, and William Shive pp 263 - 266; DOI: 10.1021/jm00308a016 |
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Antimalarials. II. .alpha.-(2-Piperidyl)- and .alpha.-(2-pyridyl)-2-trifluoromethyl-4-quinolinemethanols Roger M. Pinder and Alfred Burger pp 267 - 269; DOI: 10.1021/jm00308a017 |
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Antimalarials. III. Benzothiazole amino alcohols Alfred Burger and S. N. Sawhney pp 270 - 273; DOI: 10.1021/jm00308a018 |
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Antimalarials. IV. New synthesis of .alpha.-(2-pyridyl)- and .alpha.-(2-piperidyl)-2-aryl-4-quinolinemethanols David W. Boykin, Appasaheb R. Patel, and Robert E. Lutz pp 273 - 277; DOI: 10.1021/jm00308a019 |
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Fluorine-containing 4-quinolinemethanols as antimalarials Andrew J. Saggiomo, Kazuo Kato, and Toyo Kaiya pp 277 - 281; DOI: 10.1021/jm00308a020 |
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Chemotherapeutic nitroheterocycles. Nitropyrrole-2-carboxaldehyde derivatives William T. Colwell, Judy H. Lange, and David W. Henry pp 282 - 285; DOI: 10.1021/jm00308a021 |
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Synthesis and activity of some nitro steroids Manfred Ernst Wolff and Robert C. Boguslaski pp 285 - 287; DOI: 10.1021/jm00308a022 |
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Solvolysis of 19-hydroxy steroid derivatives William G. Dauben and David A. Ben-Efraim pp 287 - 291; DOI: 10.1021/jm00308a023 |
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Synthesis of hormone analogs containing the p-hydroxybenzyl group Don M. Lynch and Wayne Cole pp 291 - 295; DOI: 10.1021/jm00308a024 |
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Potential antitumor agents. VI. Bisquaternary salts G. J. Atwell and Bruce F. Cain pp 295 - 300; DOI: 10.1021/jm00308a025 |
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Potential antitumor agents. VII. Bisquaternary salts G. J. Atwell, Bruce F. Cain, and Ralph N. Seelye pp 300 - 305; DOI: 10.1021/jm00308a026 |
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Potential antileukemic and immunosuppressive drugs. Preparation and in vitro pharmacological activity of some 2,1,3-benzoxadiazoles (benzofurazans) and their N-oxides (benzofuroxans) P. B. Ghosh and Michael W. Whitehouse pp 305 - 311; DOI: 10.1021/jm00308a027 |
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Hexahydropyrimidines. VIII. Synthesis of 2-substituted 1,3-bis[4[N,N-bis(2-chloroethyl)amino]benzyl]hexahydropyrimidines as transport molecules for tumor inhibition John H. Billman and M. Sami Khan pp 312 - 314; DOI: 10.1021/jm00308a028 |
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Preparation and screening of aminoacridines for induction of lung tumor fluorescence in rats Norman B. Ackerman, David K. Haldorsen, Frank H. Tendick, and Edward F. Elslager pp 315 - 321; DOI: 10.1021/jm00308a029 |
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Pyrazine diuretics. V. N-Amidino-3-aminopyrazinecarboxamidines and analogous 2,4-diaminopteridines James Holden Jones and Edward J. Cragoe pp 322 - 325; DOI: 10.1021/jm00308a030 |
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Antidepressants. Tetrabenazine-antagonizing activity in a series of 5H-dibenzo[cycloheptene-5-propylamines Edward L. Engelhardt, Marcia E. Christy, C. Dylion Colton, Mark B. Freedman, Carole C. Boland, Lawrence M. Halpern, Vernon G. Vernier, and Clement Addison Stone pp 325 - 332; DOI: 10.1021/jm00308a031 |
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Synthesis and central nervous system depressant activity of new piperazine derivatives. I R. B. Petigara, Chimanlal V. Deliwala, S. S. Mandrekar, and Uttamchand K. Sheth pp 332 - 336; DOI: 10.1021/jm00308a032 |
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Transformations in the morphine series. II. New postion isomer of dihydromorphinone Lewis J. Sargent and Bhuwan C. Joshi pp 336 - 339; DOI: 10.1021/jm00308a033 |
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Synthesis and biological properties of 1-dimethyl-amino-3-methyl-3-(3-hydroxyphenyl)butane, a potential analgetic Benjamin Pecherer, R. C. Sunbury, Lowell O. Randall, and Arnold Brossi pp 340 - 342; DOI: 10.1021/jm00308a034 |
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Antinflammatory 2-aryl-1,3-indandiones Joseph G. Lombardino and Edward H. Wiseman pp 342 - 347; DOI: 10.1021/jm00308a035 |
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4-Oxo-1,2,3,4-tetrahydroquinazolines. I. Syntheses and pharmacological properties of 2-methyl-3-aryl-4-oxo-1,2,3,4-tetrahydroquinazolines and their 1-acyl derivatives Kentaro Okumura, Toyonari Oine, Yoshihisa Yamada, Goro Hayashi, and Mototaka Nakama pp 348 - 352; DOI: 10.1021/jm00308a036 |
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Chemical and biological properties of some derivatives of cis-and trans-1-hydroxyquinolizidine James D. England, Davis Temple, and Joseph Sam pp 353 - 357; DOI: 10.1021/jm00308a037 |
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Synthesis and pharmacological evaluation of some tetrahydrooxadiazinones and some dihydroaminooxadiazines Donald L. Trepanier, John N. Eble, and Guy H. Harris pp 357 - 360; DOI: 10.1021/jm00308a038 |
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Syntheses and pharmacological activity of compounds related to the antidepressant, 5-(2-dimethylaminoethyl)-2,3-di-hydro-2-phenyl-1,5-benzothiazepin-4(5H)-one (thiazesim). III John Krapcho, Chester F. Turk, and Joseph J. Piala pp 361 - 364; DOI: 10.1021/jm00308a039 |
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3-Phenylrhodanines as potential antimalarial agents Leslie M. Werbel, Nancy Headen, and Edward F. Elslager pp 364 - 365; DOI: 10.1021/jm00308a040 |
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Laboratory evaluation of the photoxic potency of quinolylmethanols William E. Rothe and David P. Jacobus pp 366 - 368; DOI: 10.1021/jm00308a041 |
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Rifomycins. XLIX. Influence of the carboxyl group on the antibacterial activity of rifomycins Nicola Maggi, S. Furesz, and Piero Sensi pp 368 - 369; DOI: 10.1021/jm00308a042 |
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Bactericidal and fungicidal activity of anthranilate esters Ned D. Heindel, Thomas F. Lemke, Sally M. Lemke, and Velmer B. Fish pp 369 - 370; DOI: 10.1021/jm00308a043 |
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The preparation and histomonastatic activity of some haloethylimidazoles Dean E. Welch and Robert D. Vatne pp 370 - 371; DOI: 10.1021/jm00308a044 |
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Synthesis of cis-9-tetradecen-1-ol acetate, the sex pheromone of the fall armyworm David Warthen pp 371 - 373; DOI: 10.1021/jm00308a045 |
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Insect sex attractants. X. 5-Dodecen-1-ol acetates, analogs of the cabbage looper sex attractant David Warthen and Martin Jacobson pp 373 - 374; DOI: 10.1021/jm00308a046 |
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Compounds related to 2,4-dichlorophenoxyacetic acid and its derivatives Jorge R. Barrio pp 374 - 375; DOI: 10.1021/jm00308a047 |
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Experimentally induced phenylketonuria. III. Inhibitors of phenylalanine hydroxylase related to esculetin Joseph I. DeGraw, Michael Cory, Wilfred A. Skinner, Myna C. Theisen, and Chozo Mitoma pp 375 - 376; DOI: 10.1021/jm00308a048 |
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Steroidal analog of a tetrahydrocannabinol Raj K. Razdan, Harry G. Pars, Felix E. Granchelli, and Louis Selig Harris pp 377 - 378; DOI: 10.1021/jm00308a049 |
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Spirans. XIV. Azatrispirans Leonard M. Rice and Kenneth R. Scott pp 378 - 380; DOI: 10.1021/jm00308a050 |
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Tumor-localizing agents. IV. Radioiodinated analogs of 1,1-dichloro-2,2-bis(chlorophenyl)ethane Raymond E. Counsell, V. V. Ranade, Lekhu K. Lala, and B. H. Hong pp 380 - 382; DOI: 10.1021/jm00308a051 |
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Phosphorus-nitrogen compounds. IX. Hydroxylamine derivatives Lindley A. Cates pp 382 - 383; DOI: 10.1021/jm00308a052 |
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2-Fluoroethylamines. III. Some alkylating agents derived from uracil Abelardo P. Martinez, William W. Lee, and Leon Goodman pp 384 - 387; DOI: 10.1021/jm00308a053 |
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Pyrimidines. XXII. 2,4-Diamino-6-arylamino-5-pyrimidinecarboxaldehydes and related compounds Darrell E. O'Brien, Louis T. Weinstock, and C. C. Cheng pp 387 - 388; DOI: 10.1021/jm00308a054 |
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Substituted 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolines Cheuk-Man Lee pp 388 - 390; DOI: 10.1021/jm00308a055 |
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Hypocholesteremic agents. IV. Substituted piperazines Howard Bernard Wright and Donald Lyons Martin pp 390 - 391; DOI: 10.1021/jm00308a056 |
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Drugs acting on the central nervous system. Syntheses of substituted quinazolinones and quinazolines and triazepino- and triazocinoquinazolinones C. M. Gupta, A. P. Bhaduri, and N. M. Khanna pp 392 - 395; DOI: 10.1021/jm00308a057 |
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3a,4,5,6-Tetrahydrosuccinimido[3,4-b]acenaphten-10-one. A potent anticonvulsant Ernest Campaigne, Wendell L. Roelofs, and Richard F. Weddleton pp 395 - 396; DOI: 10.1021/jm00308a058 |
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5,11-Dihydrodibenz[b,e][1,4]oxazepine-5-carboxamides. Compounds potentially useful in the treatment of epilepsy and trigeminal neuralgia Harry L. Yale pp 396 - 397; DOI: 10.1021/jm00308a059 |
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Inhibition of monoamine oxidase by N-(phenoxyethyl)cyclopropylamines. Correlation of inhibition with Hammett constants and partition coefficients Ray W. Fuller, Max M. Marsh, and Jack Mills pp 397 - 398; DOI: 10.1021/jm00308a060 |
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2,8-Substituted 4-methyl-1 (2H)-phthalazinones Jacob Finkelstein and John A. Romano pp 398 - 399; DOI: 10.1021/jm00308a061 |
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Stability of pyruvaldehyde bis(thiosemicarbazone) and its copper chelate James G. Cappuccino, Masao Arakawa, and M. Earl Balis pp 399 - 401; DOI: 10.1021/jm00308a062 |
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New nitrosamines Carl Tabb Bahner, David Brotherton, and Mary Karasek Brotherton pp 401 - 402; DOI: 10.1021/jm00308a063 |
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DL-2-Indaneglycine and DL-.beta.-trimethylsilylalanine Thomas Hugh Porter and William Shive pp 402 - 403; DOI: 10.1021/jm00308a064 |
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Phenyl ester of lactic acid George H. Denny, Arthur J. Zambito, and Robert D. Babson pp 403 - 403; DOI: 10.1021/jm00308a065 |
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Analgestic activity of 1-substituted 2,5-diphenylpyrroles Norman W. Gabel pp 403 - 404; DOI: 10.1021/jm00308a066 |
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Some 6,8-dibromo-S-substituted-2-mercapto-3-aryl(or alkyl)-4-quinazolones P. N. Bhargava and M. R. Chaurasia pp 404 - 405; DOI: 10.1021/jm00308a067 |
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Schiff bases containing quinoline rings Carl Tabb Bahner, David Brotherton, and Mary Karasek Brotherton pp 405 - 406; DOI: 10.1021/jm00308a068 |
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Optical resolution of iodopanoic acid Davide Pitre and Sergio Boveri pp 406 - 406; DOI: 10.1021/jm00308a069 |
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Medicinal Research Series. Volume 1. Drugs Affecting the Peripheral Nervous System Calvin M. Foltz pp 407 - 407; DOI: 10.1021/jm00308a900 |
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Neuroendocrinology. Volume 1 Erwin P. Vollmer pp 407 - 407; DOI: 10.1021/jm00308a901 |
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Insect Colonization and Mass Production Alexej B. Borkovec pp 407 - 408; DOI: 10.1021/jm00308a902 |
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Handbook of Non-Prescription Drugs Alfred Burger pp 408 - 408; DOI: 10.1021/jm00308a903 |
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Mass Spectrometry of Organic Compounds Francis A. Caren pp 408 - 408; DOI: 10.1021/jm00308a904 |
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1,4-Cycloaddition Reactions. The Diels-Alder Reaction in Heterocyclic Syntheses Francis A. Caren pp 408 - 408; DOI: 10.1021/jm00308a905 |
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Lipids and Lipidoses Jerry A. Weisbach pp 408 - 409; DOI: 10.1021/jm00308a906 |
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Annual Reports of Medicinal Chemistry, 1966 Alfred Burger pp 409 - 409; DOI: 10.1021/jm00308a907 |
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Biosynthetic Patterns in Microorganisms and Higher Plants Alfred Burger pp 409 - 409; DOI: 10.1021/jm00308a908 |
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New Drugs Alfred Burger pp 409 - 409; DOI: 10.1021/jm00308a909 |
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Quimica Farmaceutica Alfred Burger pp 409 - 410; DOI: 10.1021/jm00308a910 |
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Fluorescence: Theory, Instrumentation, and Practice W.W. Harrison pp 410 - 410; DOI: 10.1021/jm00308a911 |
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Novel antituberculosis and antileprotic agents. 1-[3-[[5,6,7,8-tetrahydro-4-(phenylazo- and 3-pyridylazo)-1-naphthyl]amino]propyl]piperidines and related compounds Leslie M. Werbel, Edward F. Elslager, Myron W. Fisher, Zoe B. Gavrilis, and Annette A. Phillips pp 411 - 419; DOI: 10.1021/jm00309a001 |
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Antiprotozoal quinones. I. Synthesis of 2-hydrox[-3-alkyl-1,4-naphthoquinones as potential coccidiostats Frank J. Bullock pp 419 - 424; DOI: 10.1021/jm00309a002 |
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Antimarlarials. Substituted 2-phenyl-4-quinolinemethanols J. S. Gillespie, Russell J. Rowlett, and Richard E. Davis pp 425 - 429; DOI: 10.1021/jm00309a003 |
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Structure-activity correlations for antibacterial agents on gram-positive and gram-negative cells Eric J. C. Lien, Corwin Hansch, and Susan M. Anderson pp 430 - 441; DOI: 10.1021/jm00309a004 |
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Molecular orbital calculations of the preferred conformations of histamine and a theory on its dual activity Lemont B. Kier pp 441 - 445; DOI: 10.1021/jm00309a005 |
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Sulfur and selenium compounds related to acetyl-choline and choline. VII. Isologs of benzoylthionocholine and of 2-dimethylaminoethyl thionobenzoate Shih- Hsi Chu and Henry G. Mautner pp 446 - 447; DOI: 10.1021/jm00309a006 |
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DL-.beta.-N,N-Dialkylaminoethyl esters of substituted .alpha.-trimethylsilylphenyl-.beta.-hydroxypropionic acids Igal Belsky, David Gertner, and A. Zilkha pp 448 - 450; DOI: 10.1021/jm00309a007 |
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Amides of silicon-containing aromatic carboxylic acids Igal Belsky, David Gertner, and Albert Zilkha pp 451 - 453; DOI: 10.1021/jm00309a008 |
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Syntheses and hypotensive activities of 3-amino-4H-pyrrolo[3,4-c]isoxazoles and derivatives Shreekrishna M. Gadekar, Sophia Nibi, Bernard D. Johnson, Elliott Cohen, and John R. Cummings pp 453 - 456; DOI: 10.1021/jm00309a009 |
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3-Substituted 1,4-benzodiazepin-2-ones Stanley C. Bell, Ronald J. McCaully, Carl Gochman, Scott J. Childress, and Melvyn I. Gluckman pp 457 - 461; DOI: 10.1021/jm00309a010 |
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Substitution in the hydantoin ring. VII. N-3-propionic acid and its ethyl ester and N-3-(2-cyanoethyl) derivatives John W. Shaffer, Eric Steinberg, Victor Krimsley, and Meldrum B. Winstead pp 462 - 466; DOI: 10.1021/jm00309a011 |
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Analgetics based on the azetidine ring D. C. Bishop, J. F. Cavalla, I. M. Lockhart, M. Wright, C. V. Winder, A. Wong, and M. Stephens pp 466 - 470; DOI: 10.1021/jm00309a012 |
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Analgetics based on .alpha.-phenyl-3-pyrrolidineacetic acid Albert D. Cale and Carl D. Lunsford pp 470 - 471; DOI: 10.1021/jm00309a013 |
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Analgetics. Esters of 3-pyrrolidinemethanols Grover C. Helsley, John A. Richman, Carl D. Lunsford, Herndon Jenkins, Richard P. Mays, William H. Funderburk, and David N. Johnson pp 472 - 475; DOI: 10.1021/jm00309a014 |
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Irreversible enzyme inhibitors. CXVI. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-substituted 2,4-diamino-5-phenylpyrimidines. 3 Bernard Randall Baker, Ping Cheong Huang, and Rich B. Meyer pp 475 - 482; DOI: 10.1021/jm00309a015 |
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Irreversible enzyme inhibitors. CXVII. Hydrophobic bonding to dihydrofolic reductase. II. Comparison of the enzyme from Walker 256, rat liver, and L1210 mouse leukemia Bernard Randall Baker pp 483 - 486; DOI: 10.1021/jm00309a016 |
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Irreversible enzyme inhibitors. CXVIII. Hydrophobic bonding to dihydrofolic reductase. 12. Further comparisons with the enzyme from Walker 256 rat tumor and rat liver Bernard Randall Baker and Morris Alfred Johnson pp 486 - 488; DOI: 10.1021/jm00309a017 |
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Irreversible enzyme inhibitors. CXIX. Active-site-directed irreversible inhibitors of dihydrofolic reductase with tissue specificity derived from 2,4,6-triaminopyrimidine with a terminal sulfonyl fluoride at the 5 position Bernard Randall Baker and Rich B. Meyer pp 489 - 494; DOI: 10.1021/jm00309a018 |
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Irreversible enzyme inhibitors. CXX. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-substituted 2,3-diamino-5-phenylpyrimidines with tissue specificity B. R. Baker and Ping Cheong Huang pp 495 - 500; DOI: 10.1021/jm00309a019 |
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Potential anticancer agents. IV. Nitrogen mustards of methylbenzoic acids I. Niculescu-Duvaz, Michaela Ionescu, A. Cambanis, M. Vitan, and V. Feyns pp 500 - 503; DOI: 10.1021/jm00309a020 |
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Some N-sulfinylhydrazine analogs of nitrogen mustard Walter T. Smith and Wen Yean Chen pp 504 - 505; DOI: 10.1021/jm00309a021 |
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Fluorinated pyrimidine aldehydes. Inhibition of nucleic acid and protein biosynthesis in Ehrlich ascites carcinoma cells in vitro Chi-Bom Chae, J. Logan Irvin, and Claude Piantadosi pp 506 - 513; DOI: 10.1021/jm00309a022 |
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Synthesis and biological activity of some 8-aza-9-cyclopentylpurines Pauline K. Chang, Louis J. Sciarini, Alan C. Sartorelli, and Morris S. Zedeck pp 513 - 515; DOI: 10.1021/jm00309a023 |
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Purine thioglycosides. I. S-Glycosides of 6-mercaptopurine Irving Goodman, Ludwig Salce, and George H. Hitchings pp 516 - 521; DOI: 10.1021/jm00309a024 |
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The synthesis and biological properties of hydroxylaminopurines and related derivatives A. Giner-Sorolla, S. A. O'Bryant, C. Nanos, M. R. Dollinger, A. Bendich, and J. H. Burchenal pp 521 - 523; DOI: 10.1021/jm00309a025 |
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Enzymic and chemical synthesis of 1-.beta.-D-arabinofuranosyl-5-fluoropyrimidine 5'-phosphates. A comparative study W. Strider, C. Harvey, and A. L. Nussbaum pp 524 - 527; DOI: 10.1021/jm00309a026 |
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Cholinesterase hydrolysis and substrate inhibition of lactoylcholines B. V. Rama Sastry and Eve C. White pp 528 - 533; DOI: 10.1021/jm00309a027 |
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Synthesis and pharmacology of a series of 1-aralkyl-3-butenylamines F. J. McCarty, Paul Daniel Rosenstock, J. P. Paolini, D. D. Micucci, L. Ashton, Walter W. Bennetts, and F. P. Palopoli pp 534 - 541; DOI: 10.1021/jm00309a028 |
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Pteridines. V. Some analogs of 4,7-diamino-2-phenyl-6-pteridinecarboxamide Joseph Weinstock, Roberta Y. Dunoff, and June G. Williams pp 542 - 548; DOI: 10.1021/jm00309a029 |
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Pteridines. VI. Preparation of some 6-aryl-7-aminopteridines Joseph Weinstock, Roberta Y. Dunoff, Blaine Sutton, Barry Trost, Joel Kirkpatrick, Frank Farina, and Alice S. Straub pp 549 - 556; DOI: 10.1021/jm00309a030 |
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Pteridines. VII. Some 2,4-diamino-6-phenylpteridines Joseph Weinstock, Irwin J. Pachter, Piroska E. Nemeth, and Gerald Jaffe pp 557 - 560; DOI: 10.1021/jm00309a031 |
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Pteridines. VIII. Some 2,4,7-triamino-6-heteroarylpteridines Joseph Weinstock, Harold Graboyes, Gerald Jaffe, Irwin J. Pachter, Kenneth Snader, Carole B. Karash, and Roberta Y. Dunoff pp 560 - 564; DOI: 10.1021/jm00309a032 |
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Pteridines. IX. Some pteridine isomers of triamterene Joseph Weinstock and Roberta Y. Dunoff pp 565 - 568; DOI: 10.1021/jm00309a033 |
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Pteridines. X. Some pyrimidopyrimidine isomers of triamterene Harold Graboyes, Gerald E. Jaffe, Irwin J. Pachter, Joanne P. Rosenbloom, Anthony J. Villani, James W. Wilson, and Joseph Weinstock pp 568 - 573; DOI: 10.1021/jm00309a034 |
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Pteridines. XII. Structure-activity relation of some pteridine diuretics Joseph Weinstock, James W. Wilson, Virgil D. Wiebelhaus, Alfred R. Maass, Francis T. Brennan, and Genevieve Sosnowski pp 573 - 579; DOI: 10.1021/jm00309a035 |
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Synthesis of substituted 4-dimethylaminoazobenzenes and a study of their effect of Lactobacillus casei and Escherichia coli Girgis M. Bebawi and J. P. Lambooy pp 580 - 582; DOI: 10.1021/jm00309a036 |
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Potential folic acid antagonists. III. The antitumor and folate reductase inhibitory properties of some irreversibly acting 6-N-substituted 2,4,6-triamino-5-(4-carbethoxyphenylazo)pyrimidines J. Hampshire, P. Hebborn, A. M. Triggle, and D. J. Triggle pp 583 - 588; DOI: 10.1021/jm00309a037 |
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Peptides of pyrimidine amino acids Chung Il Hong, Claude Piantadosi, and J. Logan Irvin pp 588 - 591; DOI: 10.1021/jm00309a038 |
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2,6-Dialkylpiperazines. IV. 1-Propionyl-4-substituted cis-2,6-dimethylpiperazines structurally related to the analgetic 8-acyl-3,8-diazabicyclo[3.2.1] octanes Giorgio Cignarella and Emilio Testa pp 592 - 594; DOI: 10.1021/jm00309a039 |
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Chemorelease of norepinephrine from mouse hearts. III. 3,5-Dihydroxy-4-methoxyphenethylamines and related compounds Cyrus R. Creveling, John W. Daly, and Bernhard Witkop pp 595 - 596; DOI: 10.1021/jm00309a040 |
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The chemorelease of norepinephrine from mouse hearts. IV. Structure-activity relations. Reserpines and yohimbines Cyrus R. Creveling, John W. Daly, R. T. Parfitt, and Bernhard Witkop pp 596 - 598; DOI: 10.1021/jm00309a041 |
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The toxicity of several cyclopentylamino acid analogs C. J. Abshire pp 598 - 599; DOI: 10.1021/jm00309a042 |
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Some arylalkylamino analogs of acyclic analgetics A. F. Casy and M. M. A. Hassan pp 599 - 601; DOI: 10.1021/jm00309a043 |
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Configurational influences in methadol and normethadol analgetics Alan F. Casy and M. M. A. Hassan pp 601 - 603; DOI: 10.1021/jm00309a044 |
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7-Oxabicyclo[2.2.1]heptane-2,3-dicarboximides with anticonvulsant activity Earl R. Bockstahler, Lawrence C. Weaver, and Donald L. Wright pp 603 - 606; DOI: 10.1021/jm00309a045 |
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Hypotensive quaternary ammonium salts with a guaiacol or thymol residue M. Carissimi, A. Cattaneo, R. D'Ambrosio, E. Grumelli, E. Milla, and F. Ravenna pp 606 - 608; DOI: 10.1021/jm00309a046 |
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Substituted heteroaromatic anthranilic acids with antiinflammatory activity E. Falch, J. Weis, and T. Natvig pp 608 - 611; DOI: 10.1021/jm00309a047 |
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o-Acetoxyphenylacetic acid, an aspirin homolog Alex Gringauz pp 611 - 612; DOI: 10.1021/jm00309a048 |
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2,6-Dialkylpiperazines. V. Synthesis of 2,6-alkylpiperazine derivatives structurally related to cinnarazine Giorgio Cignarella and Emilio Testa pp 612 - 615; DOI: 10.1021/jm00309a049 |
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3-Hydroxy-1-methyl-4-(diphenylmethylene)piperidine J. Martin Grisar, Kenneth R. Hickey, Donald R. Meyer, and Alan C. Levy pp 615 - 616; DOI: 10.1021/jm00309a050 |
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Dihydropyrrolo[3,4-c]pyrazoles Shreekrishna M. Gadekar, Bernard D. Johnson, and Elliott Cohen pp 616 - 618; DOI: 10.1021/jm00309a051 |
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Pteridines. XI. Pteridines related to the diuretic, 2,4-diamino-6,7-dimethylpteridine Joseph Weinstock, Roberta Y. Dunoff, Joyce E. Carevic, June G. Williams, and Anthony J. Villani pp 618 - 620; DOI: 10.1021/jm00309a052 |
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Antitumor and antimicrobial screening of crosemperine, the otonecine ester occurring in Crotalaria semperflorenes. II Rameshwar Kumar Sharma and Peter Hebborn pp 620 - 621; DOI: 10.1021/jm00309a053 |
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Cytostatic bis(haloacyl) derivatives of piperazine and 2-methylpiperazine Stefan Groszkowski, Juliusz Sienkiewicz, Liliana Najman, Rodica Oteleanu, and Maria Retexeanu pp 621 - 622; DOI: 10.1021/jm00309a054 |
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Nitrogen mustard derivatives in the phenothiazine and benzophenothiazine series T. Gerald Jackson and David A. Shirley pp 622 - 623; DOI: 10.1021/jm00309a055 |
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Cysteine analogs as potential amino acid antagonists in bacteria Walter A. Zygmunt and Tellis A. Martin pp 623 - 625; DOI: 10.1021/jm00309a056 |
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N-Acylcysteines Tellis A. Martin, David H. Causey, and John R. Corrigan pp 625 - 627; DOI: 10.1021/jm00309a057 |
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The anticancer and antimalarial properties and preparation of arylazopyrimidines Robert E. Harmon, Frederic E. Dutton, and H. Dale Warren pp 627 - 629; DOI: 10.1021/jm00309a058 |
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Potential antimalarial agents. 2-[[(Dialkylamino)alkyl] amino] -3-(2-pyridyl)quinoxalines Edward F. Elslager, Carolyn A. Hess, and Leslie M. Werbel pp 630 - 631; DOI: 10.1021/jm00309a059 |
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Antimalarial agents. I. Reduction of sydnone derivatives Ivan C. Popoff and Gopal H. Singhal pp 631 - 633; DOI: 10.1021/jm00309a060 |
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11-Alkylated steroids. VI. 11.beta.-hydroxy-11.alpha.-methyl-5.beta.-pregnan-20-one Gunther S. Fonken and William J. Wechter pp 633 - 634; DOI: 10.1021/jm00309a061 |
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Some derivatives of 1-aminoadamantane C. Podesva and C. Solomon pp 634 - 635; DOI: 10.1021/jm00309a062 |
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6H-Indeno[2,1-g]quinolines B. R. T. Keene and G. C. Mannering pp 635 - 635; DOI: 10.1021/jm00309a063 |
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Substituted quinazolinone hydrazides as possible antituberculous agents Surendra S. Parmar and R. Kumar pp 635 - 636; DOI: 10.1021/jm00309a064 |
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Heterocycles. III. Syntheses of N-tosyl-3-carbomethoxy-3-methyl-4-oxo-1,2,3,4-tetrahydroquinoline and N-tosyl-3-cyano-3-methyl-4-oxo-1,2,3,4-tetrahydroquinoline Tosio Moriwake and Hirosi Namba pp 636 - 637; DOI: 10.1021/jm00309a065 |
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Terpene compounds as drugs. IV. Terpenyl derivatives of local anesthetics Antonio Mantegani, Ernesta Marazzi-Uberti, and Ermanno Zugna pp 637 - 637; DOI: 10.1021/jm00309a066 |
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Mannich bases of 4-(methylthio)phenol and 3-methyl 4-(methylthio)phenol Milton J. Kornet and Mary Jane Lawrence pp 637 - 638; DOI: 10.1021/jm00309a067 |
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Irreversible enzyme inhibitors. CXXI. Thymidine phosphorylase. 9. Nature and dimensions of the hydrophobic bonding region B. R. Baker and Waclaw Rzeszotarski pp 639 - 644; DOI: 10.1021/jm00310a001 |
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Irreversible enzyme inhibitors. CXXII. Nature and dimensions of the hydrophobic bonding region of guanine deaminase and xanthine oxidase B. R. Baker and William F. Wood pp 644 - 649; DOI: 10.1021/jm00310a002 |
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Irreversible enzyme inhibitors. CXXIII. Candidate irreversible inhibitors of guanine deaminase and xanthine oxidase derived from 9-phenylguanine substituted with a terminal sulfonyl fluoride B. R. Baker and William F. Wood pp 650 - 652; DOI: 10.1021/jm00310a003 |
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Irreversible enzyme inhibitors. CXXIV. Active site-directed irreversible inhibitors of xanthine oxidase derived from 2- (and 8-) benzylthiopurines bearing a terminal sulfonyl fluoride B. R. Baker and Janos A. Kozma pp 652 - 655; DOI: 10.1021/jm00310a004 |
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Irreversible enzyme inhibitors. CXXV. Active site-directed irreversible inhibitors of xanthine oxidase derived from arylpurines and pyrazolo[3,4-d]pyrimidines bearing a terminal sulfonyl fluoride B. R. Baker and Janos A. Kozma pp 656 - 661; DOI: 10.1021/jm00310a005 |
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Irreversible enzyme inhibitors. CXXVI. Hydrocarbon interaction with xanthine oxidase by phenyl substituents on purines and pyrazolo[3,4-d]pyrimidines B. R. Baker, William F. Wood, and Janos A. Kozma pp 661 - 666; DOI: 10.1021/jm00310a006 |
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Irreversible enzyme inhibitors. CXXVII. p-(2,6-Diamino-1,2-dihydro-2,2-dimethyl-s-triazin-l-yl)phenylpropionylsulfanilyl fluoride, an active site-directed irreversible inhibitor of dihydrofolic reductase. 3. Effects of modification of the propionamide bridge on isozyme specificity B. R. Baker and Gerhardus J. Lourens pp 666 - 672; DOI: 10.1021/jm00310a007 |
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Irreversible enzyme inhibitors. CXXVIII. p-(4,6-Diamino-1,2-dihydro-2,2-dimethyl-s-triazin-l-yl)phenylpropionylsulfanilyl fluoride, an active site-directed irreversible inhibitor of dihydrofolic reductase. 4. Effects of substitution on the propionamide bridge on isozyme specificity B. R. Baker and Gerhardus J. Lourens pp 672 - 677; DOI: 10.1021/jm00310a008 |
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Irreversible enzyme inhibitors. CXXIX. p-(4,6-Diamino-1,2-dihydro-2,2-dimethyl-s-triazine-l-yl)phenylpropionylsulfanilyl fluoride, an active site-directed irreversible inhibitor of dihydrofolic reductase. 5. Effects of substitution on the benzenesulfonyl fluoride moiety on isozyme specificity B. R. Baker and Gerhardus J. Lourens pp 677 - 682; DOI: 10.1021/jm00310a009 |
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Irreversible enzyme inhibitors. CXXX. Cytosine nucleoside deaminase. 1. Hydrophobic bonding with monosubstituted uracils Bernard R. Baker and James L. Kelley pp 682 - 686; DOI: 10.1021/jm00310a010 |
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Irreversible enzyme inhibitors. CXXXI. Cytosine nucleoside deaminase. 2. Hydrophobic bonding with disubstituted uracils and cytosines B. R. Baker and James L. Kelley pp 686 - 690; DOI: 10.1021/jm00310a011 |
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Potential antitumor agents. VIII. Bisquaternary salts G. J. Atwell, B. F. Cain, and R. N. Seelye pp 690 - 694; DOI: 10.1021/jm00310a012 |
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Metal complexes of 3-ethoxy-2-oxobutyraldehyde bis(thiosemicarbazone) and related ligands as antitumor agents G. J. Van Giessen and H. G. Petering pp 695 - 699; DOI: 10.1021/jm00310a013 |
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Potential antitumor agents. I. A series of 5-substituted 1-formylisoquinoline thiosemicarbazones Krishna C. Agrawal, Barbara A. Booth, and Alan C. Sartorelli pp 700 - 703; DOI: 10.1021/jm00310a014 |
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Condensed pyrimidine systems. XXIII. Synthesis of 2,4-diaminopyrido[2,3-d]pyrimidines from .beta.-oxo esters B. S. Hurlbert, K. W. Ledig, P. Stenbuck, B. F. Valenti, and G. H. Hitchings pp 703 - 707; DOI: 10.1021/jm00310a015 |
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Condensed pyrimidine systems. XXIV. The condensation of 2,4,6-triaminopyrimidine with malondialdehyde derivatives B. S. Hurlbert and B. F. Valenti pp 708 - 710; DOI: 10.1021/jm00310a016 |
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Condensed pyrimidine systems. XXV. 2,4-Diaminopyrido[2,3-d]pyrimidines. Biological data B. S. Hurlbert, R. Ferone, T. A. Herrmann, G. H. Hitchings, Margaret Barnett, and S. R. M. Bushby pp 711 - 717; DOI: 10.1021/jm00310a017 |
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Synthesis and biological activity of some N6-alkyladenosines M. H. Fleysher, M. T. Hakala, A. Bloch, and R. H. Hall pp 717 - 720; DOI: 10.1021/jm00310a018 |
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Antiviral agents. I. Analogs and derivatives of 2-diethylaminoethyl 4-methylpiperazine-1-carboxylate Robert B. Angier, K. C. Murdock, William V. Curran, Paula Yurkanis Sollenberger, and Jeremiah P. Casey pp 720 - 729; DOI: 10.1021/jm00310a019 |
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Structural aspects of picrotoxinin action Charles H. Jarboe, Lee A. Porter, and Robert T. Buckler pp 729 - 731; DOI: 10.1021/jm00310a020 |
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Some 4(1H)-quinolylidene and 1,8-naphthyrid-4(1H)-ylidene acetamides W. D. Podmore pp 731 - 734; DOI: 10.1021/jm00310a021 |
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New analgetic agents. V. 1-Butyryl-4-cinnamylpiperazine hydrochloride and related compounds Tsutomu Irikura, Kuniyoshi Masuzawa, Keigo Nishino, Morimichi Kitagawa, Hiroaki Uchida, Noriko Ichinoseki, and Masatoshi Ito pp 801 - 804; DOI: 10.1021/jm00310a022 |
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Analgetic activity of 4a,8a-(methaniminomethano)naphthalene derivatives Eugene R. Wagner and John N. Davisson pp 805 - 807; DOI: 10.1021/jm00310a023 |
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Synthesis and antiinflammatory screening of phenoxazine-1-carboxylic acids Benjamin Blank and Lawrence L. Baxter pp 807 - 811; DOI: 10.1021/jm00310a024 |
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Hypotensive activity of some cyanoguanidines Shreekrishna M. Gadekar, Sophia Nibi, and Elliott Cohen pp 811 - 814; DOI: 10.1021/jm00310a025 |
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The synthesis and activity of some 2,6-difluorophenyl-substituted compounds Anthony M. Roe, R. A. Burton, G. L. Willey, M. W. Baines, and A. C. Rasmussen pp 814 - 819; DOI: 10.1021/jm00310a026 |
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Heterocyclic mesoionic structures, a novel class of monoamine oxidase inhibitors. I. Arylsydnones Donald P. Cameron and Edward H. Wiseman pp 820 - 824; DOI: 10.1021/jm00310a027 |
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N-Substituted derivatives of 2-aminoethanethiol and 2-hydrazinoethanethiol Roger D. Westland, Joyce L. Holmes, Billie Green, and John R. Dice pp 824 - 829; DOI: 10.1021/jm00310a028 |
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Molecular orbital methods in the study of cholinesterase inhibitors Arthur Cammarata and Richard L. Stein pp 829 - 833; DOI: 10.1021/jm00310a029 |
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N-sec- and N-tert-Alkyl derivatives of methoxamine and related compounds Richard Baltzly and Nariman B. Mehta pp 833 - 844; DOI: 10.1021/jm00310a030 |
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Adrenergic neurone blocking agents. III. Heterocyclic analogs of guanoxan J. Augstein, A. M. Monro, G. W. H. Potter, and P. Scholfield pp 844 - 848; DOI: 10.1021/jm00310a031 |
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Sympathetic nervous system blocking agents. IV. Synthesis of 2-[2-(methylthio)ethylamino]ethylguanidine sulfate and related compounds James H. Short and Thomas D. Darby pp 848 - 854; DOI: 10.1021/jm00310a032 |
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The synthesis of substituted phenethylamines Stephen Raines and Csaba A. Kovacs pp 854 - 856; DOI: 10.1021/jm00310a033 |
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Silicon-containing phenethylamines Max Frankel, Mordechai Broze, David Gertner, Avner Rotman, Avinoam Shenhar, and Albert Zilkha pp 857 - 860; DOI: 10.1021/jm00310a034 |
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A conformational study of .beta.-phenethanolamine receptor sites. I. The syntheses of the 3-amino-2-phenyl-trans-2-decalols Edward E. Smissman and William H. Gastrock pp 860 - 864; DOI: 10.1021/jm00310a035 |
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Synthesis and myotrophic-androgenic activity of substituted 2.alpha.,3.alpha.-methano-5.alpha.-androstane derivatives Manfred E. Wolff, Sheue-Yann Cheng, and Winston Ho pp 864 - 868; DOI: 10.1021/jm00310a036 |
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Methylenation of unsaturated ketones. VI. Synthesis of 6,7-difluoromethylene corticoids I. T. Harrison, C. Beard, L. Kirkham, B. Lewis, I. M. Jamieson, W. Rooks, and J. H. Fried pp 868 - 871; DOI: 10.1021/jm00310a037 |
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Analogs of steroid hormones. II. 6-(Cyclopentyl) derivatives of 2-naphthalenone R. E. Juday, Lynette Cubbage, Judith Mazur, and Bonnie Bukwa pp 872 - 875; DOI: 10.1021/jm00310a038 |
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The synthesis and biological evaluation of 16.beta.-amino-17.alpha.-hydroxy-20-oxopregnenes Clarence G. Bergstrom pp 875 - 879; DOI: 10.1021/jm00310a039 |
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17-Aminoacylamido-5-androsten-3.beta.-ols George Flouret and Wayne Cole pp 880 - 882; DOI: 10.1021/jm00310a040 |
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The mitomycin antibiotics. Synthetic studies. XX. N-Substituted carbamoyl and acyl esters of a related 3-(hydroxymethyl)indole-4,7-dione John F. Poletto, George R. Allen, and Martin J. Weiss pp 882 - 885; DOI: 10.1021/jm00310a041 |
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Adamantane derivatives of p-aminobenzamide and sulfanilamide S. F. Zakrzewski, A. Bloch, and C. A. Nichol pp 885 - 886; DOI: 10.1021/jm00310a042 |
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Antimalarial agents. III. Bis[p-(3-sydnonyl)phenyl] sulfone Ivan C. Popoff and Gopal H. Singhal pp 886 - 887; DOI: 10.1021/jm00310a043 |
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The photoactivity of quinolinemethanols I. Gordon Fels pp 887 - 888; DOI: 10.1021/jm00310a044 |
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Active structures in the 2-aminoethylbenzimidazoles series M. Mousseron, J. M. Kamenka, and A. Stenger pp 889 - 894; DOI: 10.1021/jm00310a045 |
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5-(Dimethylaminopropyl)-10,11-dihydro-5H-benzo[2,3]pyrido[6,7-b]azepine Frank J. Villani and Thomas A. Mann pp 894 - 895; DOI: 10.1021/jm00310a046 |
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The synthesis and pharmacological properties of dibenz[b,e][1,4]oxazepin-11(5H)-ones Stephen Raines, Csaba A. Kovacs, Sidney Goldstein, and Frank P. Palopoli pp 895 - 896; DOI: 10.1021/jm00310a047 |
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The chemorelease of norepinephrine from mouse hearts by substituted amphetamines F. Benington and R. D. Morin pp 896 - 897; DOI: 10.1021/jm00310a048 |
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Some compounds active as antirhinovirus in the plaque inhibition test Carlo Runti pp 897 - 899; DOI: 10.1021/jm00310a049 |
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The synthesis of 3,5-diisopropyl-3'-iodo-DL-thyronine Teruo Matsuura, Tomoaki Nagamachi, Kotaro Matsuo, and Akira Nishinaga pp 899 - 900; DOI: 10.1021/jm00310a050 |
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Synthesis and pharmacology of some indanamines. Dialkylaminoethylindans Samir Chandra Lahiri and Nemai Chandra De pp 900 - 902; DOI: 10.1021/jm00310a051 |
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5-Aryl-2-furanacetic acids James S. Kaltenbronn and Tae O. Rhee pp 902 - 902; DOI: 10.1021/jm00310a052 |
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The preparation and pharmacology of some 11.beta.-hydroxy-4-methylestratrienes Leland J. Chinn pp 902 - 904; DOI: 10.1021/jm00310a053 |
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Drug latentiation. The preparation and preliminary pharmacological evaluation of some mephenesin aryloxyacetates F. Bottari, M. F. Saettone, and M. F. Serafini pp 904 - 907; DOI: 10.1021/jm00310a054 |
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Reduced derivatives of methotrexate S. B. Horwitz and R. L. Kisliuk pp 907 - 908; DOI: 10.1021/jm00310a055 |
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Synthesis of 6,8-dibromo-3-substituted 2-[N,N-dialkyl (or N-piperidino)carboxamidomethylthio]-4(3H)-quinazolinones as antimalarials P. N. Bhargava and M. R. Chaurasia pp 908 - 909; DOI: 10.1021/jm00310a056 |
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4-(Dialkylaminoalkylamino)-3-phenylpyridines Warren G. Duncan and David W. Henry pp 909 - 910; DOI: 10.1021/jm00310a057 |
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4-Amino-1-(.beta.-D-ribofuranosyl)benzimidazole Susan R. Jenkins, Frederick W. Holly, and Roland K. Robins pp 910 - 910; DOI: 10.1021/jm00310a058 |
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Terpene compounds as drugs. V. Terpenyl derivatives of salicylic acid Gianfranco Pala, Tiberio Bruzzese, and Bruno Lumachi pp 910 - 911; DOI: 10.1021/jm00310a059 |
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Preparation and properties of a nitrogen mustard derived from methylpyrazine Albert Hirschberg and Paul G. Mattner pp 911 - 912; DOI: 10.1021/jm00310a060 |
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9-(2-Deoxycellobiosyl)adenine Leon M. Lerner pp 912 - 912; DOI: 10.1021/jm00310a061 |
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Quinazolines and 1,4-benzodiazepines. XXXIX. The synthesis of dihydroimidazo- and tetrahydropyrimido[1,2-.alpha.][1,4]benzodiazepines M. E. Derieg, R. Ian Fryer, R. M. Schweininger, and L. H. Sternbach pp 912 - 913; DOI: 10.1021/jm00310a062 |
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Some 4H,12H-pyrano[2,3-.alpha.]phenoxazin-4-ones Satyendra Kumar pp 913 - 914; DOI: 10.1021/jm00310a063 |
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Retardation of Collagen Fibril Formation by Unsaturated Fatty Acids Norman H. Grant, and Harvey E. Alburn pp 734 - 737; DOI: 10.1021/jm00310a600 |
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The Mitomycin Antibiotics. Synthetic Studies. XXI. Indoloquinone Analogs with Further Variations at C-5. William A. Remers, and Martin J. Weiss pp 737 - 742; DOI: 10.1021/jm00310a601 |
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The Mitomycin Antibiotics. Synthetic Studies. XXII. Antibacterial Structure-Activity Relationships in the Indoloquinone Series Martin J. Weiss, Gunnar s. Redin, George R. Allen, Jr., Albert C. Dornbush, Harry L. Lindsay, John F. Poletto, William A. Remers, Reta H. Roth, and Adolf E. Slobada pp 742 - 745; DOI: 10.1021/jm00310a602 |
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Bottromycin. Separation of Biologically Active Compounds and Preparation and Testing of Amide Derivatives W. J. Miller, L. Chaiet, G. Rasmussen, B. Christensen, J. Hannah, A. Katherine Miller, and F. J. Wolfe pp 746 - 749; DOI: 10.1021/jm00310a603 |
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5,5-Diarylpenta-2,4-dienoic Acid Amides as Potential Antimalarial Agents William T. Colwell, Judy H. Lange, and David W. Henry pp 749 - 752; DOI: 10.1021/jm00310a604 |
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Synthesis and Pharmacology of Some α-Oxy- and α-Hydroxy-1-benzyltetrahydroisoquinolines Jerry A. Weisbach, Joel L Kirkpatrick, Edward Macko, and Bryce Douglas pp 752 - 760; DOI: 10.1021/jm00310a605 |
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Synthesis and Pharmacology of Some α-Keto, α-Hydroxy, α-Amino-1-benzylisoquinolines Jerry A. Weisbach, Joel L. Kirkpatrick, Edward Macko, and Bryce Douglas pp 760 - 764; DOI: 10.1021/jm00310a606 |
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Synthesis and Pharmacological Evaluation of Some Pyrrolo[2,1-α]isoquinolines Cesare Casagrande, Ambrogio Invernizzi, Rosano Ferrini, and Giorgio G. Ferrari pp 765 - 770; DOI: 10.1021/jm00310a607 |
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Urinary Metabolites of 7-Chloro-1-(2-diethylaminoethyl)-5-(2-flurophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one Dihydrochloride Morton A. Schwartz, Floie M. Vane, and Edward Postma pp 770 - 774; DOI: 10.1021/jm00310a608 |
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Quinazolines and 1,4-Benzodiazepines. XL. The Synthesis of Metabolites of 7-Chloro-1-(2-diethylaminoethyl)-5-(2-flourophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one J. V. Early, R. Ian Fryer, D. Winter, and L. H. Sternbach pp 774 - 777; DOI: 10.1021/jm00310a609 |
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Tetrahydroisoquino [2,1-d][1,4]benzodiazepines. Synthesis and Neuropharmacological Activity Hans Ott, Goetz E. Hardtmann, Max Denzer, Albert J. Frey, John H. Gogerty, George H. Leslie, and Joseph H. Trapold pp 777 - 787; DOI: 10.1021/jm00310a610 |
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4-Oxo-1,2,3,4-tetrahydroquinazolines. II. Synthesis of 1-Alkyl-and 1-[2,(Distributed amino)ethyl]-2-methyl-3-aryl-4-oxo-1,2,3,4-tetrahydroquinazolines Kentaro Okumura, Toyonari Oine, Yoshihisa Yamada, Goro Hayashi, Mototaka Nakama, and Takashi Nose pp 788 - 792; DOI: 10.1021/jm00310a611 |
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Derivatives of 3-Piperidinol as Central Stimulants Lewis A. Walter, Cecile K. Springer, Joanne Kenney, Susan K. Galen, and Nathan Sperber pp 792 - 796; DOI: 10.1021/jm00310a612 |
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4-Substituted Piperidines. IV. The Synthesis of 4-[(2,6-Dioxo-3-phenyl)-3-piperidyl]piperidines Bert Hermans, Paul Van Daele, Cornelis van de Westeringh, Cyriel Van der Eycken, Jozef Boey, Jozef Dockx, and Paul A. J. Janssen pp 797 - 800; DOI: 10.1021/jm00310a613 |
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Use of homolytic, steric, and hydrophobic constants in a structure-activity study of 1,3-benzodioxole synergists Corwin Hansch pp 920 - 924; DOI: 10.1021/jm00311a001 |
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Penicillin dipeptides Arthur M. Felix, Joel Unowsky, John Bontempo, and R. Ian Fryer pp 929 - 932; DOI: 10.1021/jm00311a002 |
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Chemistry of cephalosporins. XII. Configuration of the carboxyl group in .DELTA.2-cephalosporins E. Van Heyningen and Linda Kay Ahern pp 933 - 936; DOI: 10.1021/jm00311a003 |
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Rifamycins. LIX. Acetyl migration in rifampicin N. Maggi, A. Vigevani, G. G. Gallo, and C. R. Pasqualucci pp 936 - 939; DOI: 10.1021/jm00311a004 |
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Structure of sangivamycin Koppaka V. Rao pp 939 - 941; DOI: 10.1021/jm00311a005 |
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Synthesis of some heterocyclic derivatives of biguanide with antibacterial activity John W. James, James A. Baker, and Leslie F. Wiggins pp 942 - 945; DOI: 10.1021/jm00311a006 |
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Analogs of 3-amino-7-chloro-1,2,4-benzotriazine 1-oxide as antimalarial agents J. Kenneth Horner and David W. Henry pp 946 - 949; DOI: 10.1021/jm00311a007 |
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Synthetic schistosomicides. IX. N-(dialkylaminoalkyl)-4-nitroso-1-naphthylamines Leslie M. Werbel, Edward F. Elslager, and Donald F. Worth pp 950 - 955; DOI: 10.1021/jm00311a008 |
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Insect chemosterilants. VII. Oxidative degradation of hexamethylmelamine Albert B. DeMilo and Alexej B. Borkovec pp 961 - 963; DOI: 10.1021/jm00311a009 |
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Potential antitumor agents. IX. Bisquaternary salts B. F. Cain, G. J. Atwell, and R. N. Seelye pp 963 - 966; DOI: 10.1021/jm00311a010 |
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A kinetic study of the reaction between 1,1'-trimethylenebis(4-hydroximinomethylpyridinium) dibromide and diisopropyl phosphorofluoridate Yacov Ashani, Nathan Dinar, and Sasson Cohen pp 967 - 969; DOI: 10.1021/jm00311a011 |
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Diuretics. 4-Substituted 3-sulfamoylbenzoic acid hydrazides M. L. Hoefle, L. T. Blouin, H. A. DeWald, Ann Holmes, and Dorothy Williams pp 970 - 973; DOI: 10.1021/jm00311a012 |
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Diuretics. 3-Amino- and 3-hydroxy-7-chloro-3,4-dihydro-4-oxo-6-quinazolinesulfonamides Milton L. Hoefle and Ann Holmes pp 974 - 976; DOI: 10.1021/jm00311a013 |
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Centrally acting emetics. II. Norapomorphine and derivatives Melvin V. Koch, Joseph G. Cannon, and Allan M. Burkman pp 977 - 981; DOI: 10.1021/jm00311a014 |
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4-[3(5)-Pyrazolyl]pyridinium salts. A new class of hypoglycemic agents Victor J. Bauer, Harry P. Dalalian, William J. Fanshawe, S. R. Safir, E. C. Tocus, and C. R. Boshart pp 981 - 984; DOI: 10.1021/jm00311a015 |
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Isoxazolylpyridinium salts. A new class of hypoglycemic agents Victor J. Bauer, William J. Fanshawe, Harry P. Dalalian, and S. R. Safir pp 984 - 986; DOI: 10.1021/jm00311a016 |
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Nonsteroidal hypocholesteremic agents. II. Synthesis and serum sterol lowering properties of 4-(2-dialkylaminoalkoxy)-4'-substituted biphenyls and related compounds Frederick L. Bach, John C. Barclay, Frances Kende, and Elliott Cohen pp 987 - 993; DOI: 10.1021/jm00311a017 |
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1-[2-[4'-(Trifluoromethyl)-4-biphenylyloxy]ethyl]pyrrolidine. A potent hyposterolemic agent Samuel Gordon and Walter P. Cekleniak pp 993 - 996; DOI: 10.1021/jm00311a018 |
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Stereochemistry of 5-substituted decahydroisoquinolines and their antiarrhythmic activity Ian W. Mathison, Richard C. Gueldner, James W. Lawson, Sara J. Fowler, and Elizabeth R. Peters pp 997 - 1000; DOI: 10.1021/jm00311a019 |
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.beta.-Adrenergic blocking agents. I. Pronethalol and related N-alkyl and N-aralkyl derivatives of 2-amino-1-(2-naphthyl)ethanol Ralph Howe, A. F. Crowther, J. S. Stephenson, B. S. Rao, and L. H. Smith pp 1000 - 1008; DOI: 10.1021/jm00311a020 |
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.beta.-Adrenergic blocking agents. II. Propranolol and related 3-amino-1-naphthoxy-2-propanols A. F. Crowther and L. H. Smith pp 1009 - 1013; DOI: 10.1021/jm00311a021 |
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Potential anticancer agents. II. Schiff bases from benzaldehyde nitrogen mustards M. G. Dhapalapur, S. S. Sabnis, and C. V. Deliwala pp 1014 - 1019; DOI: 10.1021/jm00311a022 |
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Skeletal muscle stimulants. Substituted benzoic acids Robert Bruce Moffett and Andrew H. Tang pp 1020 - 1022; DOI: 10.1021/jm00311a023 |
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Synthesis and muscle-relaxing activity of o-, m-, and p-alkylsulfonylbenzamides and related isoquinoline derivatives M. S. Chodnekar and J. E. Blum pp 1023 - 1028; DOI: 10.1021/jm00311a024 |
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Synthesis and pharmacology of 2-(2-aminoethyl)imidazole (2-isohistamine) E. C. Kornfeld, Lora Wolf, T. M. Lin, and I. H. Slater pp 1028 - 1031; DOI: 10.1021/jm00311a025 |
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Metabolism of brompheniramine R. B. Bruce, L. B. Turnbull, J. H. Newman, and J. E. Pitts pp 1031 - 1034; DOI: 10.1021/jm00311a026 |
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Synthesis and biological activity of some 1-substituted 3-pyrrolidinylureas Grover C. Helsley, Bernard V. Franko, William J. Welstead, and Carl D. Lunsford pp 1034 - 1037; DOI: 10.1021/jm00311a027 |
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Synthesis of substituted 2,3-dihydro-4H-1,3-benzoxazin-4-ones and their biological activities Jacob Finkelstein and Elliot Chiang pp 1038 - 1040; DOI: 10.1021/jm00311a028 |
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Synthesis of compounds with potential psychotomimetic activity. IV Edward R. Freiter, Joseph G. Cannon, Larry D. Milne, and Leo G. Abood pp 1041 - 1045; DOI: 10.1021/jm00311a029 |
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Chemistry and pharmacology of a series of substituted 4H-pyrazino[1,2-a]pyrimidin-4-ones Donald L. Trepanier, L. W. Rampy, Kenneth L. Shriver, John N. Eble, and Philip J. Shea pp 1045 - 1048; DOI: 10.1021/jm00311a030 |
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Benzo[b]thiophene derivatives. XII. Synthesis of some 3-benzo[b]thienylalkylamines and comparison of their central nervous system activity with tryptamine isosteres Ernest Campaigne, E. S. Neiss, C. C. Pfeiffer, and R. A. Beck pp 1049 - 1054; DOI: 10.1021/jm00311a031 |
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Irreversible enzyme inhibitors. CXXXII. Proteolytic enzymes. 6. Tolerance for polar groups on the phenoxyacetanilide type of inhibitor of .alpha.-chymotrypsin B. R. Baker and Jeffrey A. Hurlbut pp 1054 - 1059; DOI: 10.1021/jm00311a032 |
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Phosphorus mustards. III. Bis(2-chloroethyl)methylphosphine oxide and bis(2-benzoxyethyl)methylphosphine D. C. Smith and A. H. Soloway pp 1060 - 1063; DOI: 10.1021/jm00311a033 |
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Synthesis and biological activity of piperidylindanes V. Paragamian and J. F. Gardocki pp 1064 - 1066; DOI: 10.1021/jm00311a034 |
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Chemistry of cephalosporin antibiotics. XI. Preparation and properties of deacetylcephaloglycin and its lactone S. Kukolja pp 1067 - 1069; DOI: 10.1021/jm00311a035 |
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Cassaine analogs. V. A distant analog of cassaine Sol J. Daum and Robert L. Clarke pp 1069 - 1070; DOI: 10.1021/jm00311a036 |
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Silicon-substituted medicinal agents. Parasympatholytic activity of 3,3-dimethyl-1-butanol carbamate and 2-trimethylsilyl-1-ethanol carbamate Ralph J. Fessenden and Roger Rittenhouse pp 1070 - 1071; DOI: 10.1021/jm00311a037 |
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Potential antimalarial substances. Antimetabolites of pantothenic acid Edward F. Elslager, Marland P. Hutt, and Leslie M. Werbel pp 1071 - 1073; DOI: 10.1021/jm00311a038 |
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Derivatives of 5-phenyl-2,4-pentadienoic acid as potential antimalarial agents Leslie M. Werbel, Nancy Headen, and Edward F. Elslager pp 1073 - 1074; DOI: 10.1021/jm00311a039 |
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Carcinogenic activity of analogs of p-dimethylaminoazobenzene. VI. Activity of the benzimidazole and benzthiazole analogs Ellis V. Brown and C. J. Sanchorawala pp 1074 - 1075; DOI: 10.1021/jm00311a040 |
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Phosphorus-nitrogen compounds. X. Sulfur analogs Lindley A. Cates pp 1075 - 1077; DOI: 10.1021/jm00311a041 |
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Some aza analogs of amino acids Tommy J. McCord, Llewellyn D. Booth, and Alvie L. Davis pp 1077 - 1078; DOI: 10.1021/jm00311a042 |
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Grignard addition to 17.alpha.-acetoxy-6.alpha.-methylprogesterone Arvin P. Shroff pp 1078 - 1079; DOI: 10.1021/jm00311a043 |
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Anabolic cyclic esters of 19-nortestosterone Richard T. Rapala, Ronnie G. Edie, Paula Korzekwa, and Russell J. Kraay pp 1079 - 1080; DOI: 10.1021/jm00311a044 |
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Synthesis of 6-hydroxy-5,8-dioxo-7-(9-hydroxy-9-n-pentyltetradecyl)carbostyril George R. Pettit and Leonard E. Houghton pp 1080 - 1082; DOI: 10.1021/jm00311a045 |
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A diethylstilbestrol ester Ronald A. Chung, K. M. Shih, and Russel W. Brown pp 1082 - 1083; DOI: 10.1021/jm00311a046 |
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Adrenocorticolytic derivatives of benz[.alpha.]anthracene J. Pataki, R. Wlos, and Young-Ja Cho pp 1083 - 1086; DOI: 10.1021/jm00311a047 |
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Hypocholesterolemic agents. Compounds related to ethyl .alpha.-(4-chlorophenoxy)-.alpha.-methylpropionate Donald T. Witiak, Thomas Chun-Lun Ho, Robert E. Hackney, and William E. Connor pp 1086 - 1089; DOI: 10.1021/jm00311a048 |
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Salicylic acid analogs of phenothiazine as antiinflammatory agents Andrew J. Saggiomo and Blaine M. Sutton pp 1089 - 1090; DOI: 10.1021/jm00311a049 |
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Synthesis of 1,4-disubstituted piperazines. II Matthew Verderame pp 1090 - 1092; DOI: 10.1021/jm00311a050 |
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A new class of analgetic-antiinflammatory agents. 2-Substituted 4,5-diphenyloxazoles E. Marchetti, G. Mattalia, and V. Rosnati pp 1092 - 1093; DOI: 10.1021/jm00311a051 |
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7-Nitro-8-quinolinols and their copper(II) complexes. Implications of the fungal spore wall as a possible barrier against potential antifungal agents Herman Gershon pp 1094 - 1096; DOI: 10.1021/jm00311a052 |
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Methyl triphosphate, a substrate for myosin adenosine triphosphatase Jean Lecocq pp 1096 - 1097; DOI: 10.1021/jm00311a053 |
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2-Hydroxy-3-naphthoic acid anilide phosphate as a fluorescent histochemical substrate for phosphatase K. C. Tsou and Sadao Matsukawa pp 1097 - 1099; DOI: 10.1021/jm00311a054 |
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A comparative bacteriostatic evaluation of the optical isomers of threo-2-dichloroacetamido-1-(4-methylsulfinylphenyl)-1,3-propanediol G. D. Diana and R. A. Cutler pp 1100 - 1102; DOI: 10.1021/jm00311a055 |
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Adamantylamines by direct amination of 1-bromoadamantane Eriks V. Krumkalns and William Pfeifer pp 1103 - 1103; DOI: 10.1021/jm00311a056 |
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Potential antidiabetics. I. 1-(2,4-Dinitrophenyl)-3,5-dimethyl-4-arylazopyrazoles H. G. Garg and Prem Pal Singh pp 1103 - 1104; DOI: 10.1021/jm00311a057 |
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Potential antidiabetics. II. 1-(2,4-Dinitrophenyl)-3-methyl-4-arylhydrazono-2-pyrazolin-5-ones H. G. Garg and Prem Pal Singh pp 1104 - 1105; DOI: 10.1021/jm00311a058 |
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Lysergic acid diethylamide (LSD) and tryptamine analogs as potential psychotomimetics Kenneth J. Liska, Vickie O. Jain, and Edward D. Purich pp 1105 - 1106; DOI: 10.1021/jm00311a059 |
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17.beta.-[4-[p-[Bis(.beta.-chloroethyl)amino]phenyl]-butanoyloxy]-4-androsten-3-one E. L. Foster and Robert T. Blickenstaff pp 1106 - 1106; DOI: 10.1021/jm00311a060 |
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Cysteine derivatives of keto steroids Robert T. Blickenstaff pp 1106 - 1106; DOI: 10.1021/jm00311a061 |
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2,2'-Hydrazobis(5-nitropyrimidines) Moshe Avramoff pp 1106 - 1107; DOI: 10.1021/jm00311a062 |
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Synthesis of 5,7-dioxo-3-methyl-5,6,7,8-tetrahydropyrimido[5,4-e]-as-triazine Kwang-Yuen Zee-Cheng and C. C. Cheng pp 1107 - 1108; DOI: 10.1021/jm00311a063 |
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Estra-1,3,5(10),15-tetraenes. I. Birch Reduction Donald K. Phillips, Peter P. Wickham, Gordon O. Potts, and Aaron Arnold pp 924 - 928; DOI: 10.1021/jm00311a600 |
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2,2-Dimethyl-3-vinylcyclobutaneacetic Acid, a Fungistatic Agent Derived from Pinene R.L. Settine, J.B. Lewis, Ruth Mayne, and G.W. Hedrick pp 955 - 957; DOI: 10.1021/jm00311a601 |
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Insect Chemosterilants. VI. Oxidation of Hexamethylphosphoric Triamide and the Synthesis of N-Formylphosphoramides Paul H. Terry, and Alexej B. Borkovec pp 958 - 961; DOI: 10.1021/jm00311a602 |
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The Conformation of 20-Oxopregnane Hormone from Molecular Orbital Calculations and a Consideration of the Cortisol Receptor Lemont B. Kier pp 915 - 919; DOI: 10.1021/jm00311a603 |
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Book Reviews Alfred Burger pp 1108 - 1110; DOI: 10.1021/jm00311a900 |
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Some electronic factors in drug-receptor interactions Arthur Cammarata pp 1111 - 1115; DOI: 10.1021/jm00312a001 |
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The stereoisomers of .alpha.-(1-aminoethyl)-m-hydroxybenzyl alcohol Walfred S. Saari, Andrew W. Raab, and Edward L. Engelhardt pp 1115 - 1117; DOI: 10.1021/jm00312a002 |
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.beta.-Adrenergic blocking agents. III. The optical isomers of pronethalol, propranolol, and several related compounds Ralph Howe and B. S. Rao pp 1118 - 1121; DOI: 10.1021/jm00312a003 |
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Some epinephrine analogs Ernst D. Bergmann and Zeev Goldschmidt pp 1121 - 1125; DOI: 10.1021/jm00312a004 |
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Succinylcholine analogs as substrates and inhibitors of pseudocholinesterase Arnold H. Beckett, C. L. Vaughan, and M. Mitchard pp 1126 - 1129; DOI: 10.1021/jm00312a005 |
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Sympathetic nervous system blocking agents. V. Derivatives of isobutyl-, tert-butyl-, and neopentylguanidine James H. Short, C. Wayne Ours, and Walter J. Ranus pp 1129 - 1135; DOI: 10.1021/jm00312a006 |
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1-Aminoacyl-2,3-dihydro-4(1H)-quinazolinone derivatives with choleretic and antifibrillatory activity G. Bonola, P. Da Re, M. J. Magistretti, E. Massarani, and I. Setnikar pp 1136 - 1139; DOI: 10.1021/jm00312a007 |
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Synthesis and antiinflammatory activity of 4-(p-biphenylyl)-3-hydroxybutyric acid and related compounds D. I. Barron, P. T. Bysouth, R. W. Clarke, A. R. Copley, O. Stephenson, D. K. Vallance, and A. M. Wild pp 1139 - 1144; DOI: 10.1021/jm00312a008 |
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Potential antihypertensive agents. II. Unsymmetrically 1,4-disubstituted piperazines. 1 Raj Nandan Prasad, Leslie R. Hawkins, and Karin Tietje pp 1144 - 1150; DOI: 10.1021/jm00312a009 |
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Synthesis and vasodilator activity of new piperazine derivatives Gilbert Regnier, R. J. Canevari, M. J. Laubie, and J. C. Le Douarec pp 1151 - 1155; DOI: 10.1021/jm00312a010 |
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Acetylenic carbamates. III. The N-cycloaliphatic derivatives Robert D. Dillard, G. A. Poore, Nelson R. Easton, M. J. Sweeney, and W. R. Gibson pp 1155 - 1158; DOI: 10.1021/jm00312a011 |
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Anticonvulsant semicarbazides William E. Coyne and John W. Cusic pp 1158 - 1160; DOI: 10.1021/jm00312a012 |
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Central nervous system depressants. III. 2-Aminoalkyl-3,3a,4,5-tetrahydroimidazo[1,5-a]quinolin-1(2H)-ones William B. Wright pp 1161 - 1164; DOI: 10.1021/jm00312a013 |
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Central nervous system depressants. IV. 2-Aminoalkyl-1,2-dihyro-3H-imidazo[1,5-a]indol-3-ones William B. Wright and Herbert J. Brabander pp 1164 - 1167; DOI: 10.1021/jm00312a014 |
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Synthesis and diuretic activity of 2-amino-4-arylamino-6-mercapto-s-triazines and related derivatives Madhusudan H. Shah, Chimanlal V. Deliwala, and U. K. Sheth pp 1167 - 1171; DOI: 10.1021/jm00312a015 |
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Synthesis and study of pyridylalanine N-oxides P. Timothy Sullivan, Marian Kester, and S. J. Norton pp 1172 - 1176; DOI: 10.1021/jm00312a016 |
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Carcinogenicity of lactones. III. The reactions of unsaturated .gamma.-lactones with L-cysteine John Bryan Jones and John M. Young pp 1176 - 1182; DOI: 10.1021/jm00312a017 |
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Potential anticancer agents. IV. 5-Substituted pyrimidine-6-carboxaldehydes and derivatives Chung Il Hong, Claude Piantadosi, Chi-Bom Chae, and J. Logan Irvin pp 1182 - 1189; DOI: 10.1021/jm00312a018 |
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N-Substituted S-2-aminoethyl thiosulfates as antiradiation agents Roger D. Westland, Joyce L. Holmes, Mary Lou Mouk, Douglas D. Marsh, Richard A. Cooley, and John R. Dice pp 1190 - 1201; DOI: 10.1021/jm00312a019 |
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Synthetic schistosomicides. X. Bis(4-arylazo-1-naphthylamines) Edward F. Elslager, David B. Capps, Dianne H. Kurtz, and Donald F. Worth pp 1201 - 1204; DOI: 10.1021/jm00312a020 |
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Anthelmintic quaternary salts. II. Thiazolium salts David L. Garmaise, C. H. Chambers, and R. C. McCrae pp 1205 - 1208; DOI: 10.1021/jm00312a021 |
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3,4-Dihydro-2(1H)-quinazolinones William E. Coyne and John W. Cusic pp 1208 - 1213; DOI: 10.1021/jm00312a022 |
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Synthesis of potential antimalarial agents. I. 6- and 6,9-Disubstituted purines Carroll Temple, Anne G. Laseter, and John A. Montgomery pp 1213 - 1215; DOI: 10.1021/jm00312a023 |
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Synthesis of potential antimalarial agents. II. 6,8-Disubstituted pyrido[2,3-b]pyrazines Carroll Temple, Jerry D. Rose, Robert D. Elliott, and John A. Montgomery pp 1216 - 1218; DOI: 10.1021/jm00312a024 |
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Cyclization of aniline-acetylenedicarboxylate adducts. A modified Conrad-Limpach method for the synthesis of potential antimalarials Ned D. Heindel, Ibrahim S. Bechara, Peter D. Kennewell, James Molnar, Cyrus J. Ohnmacht, Sally M. Lemke, and Thomas F. Lemke pp 1218 - 1221; DOI: 10.1021/jm00312a025 |
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Arylamino alcohol antimalarials. A new method for incorporating the side chain Warren G. Duncan, William T. Colwell, Carole R. Scott, and David W. Henry pp 1221 - 1223; DOI: 10.1021/jm00312a026 |
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Antimalarials. Analogs of phototoxic 2-phenyl-4-quinolinemethanols Edward R. Atkinson and Anthony J. Puttick pp 1223 - 1226; DOI: 10.1021/jm00312a027 |
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Some characteristics of two bipiperidyl mustards Charles C. Price, Koneru Prasada Rao, and Riichiro Shibakawa pp 1226 - 1226; DOI: 10.1021/jm00312a028 |
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Pyrimidine derivatives with antiamoebic activity Dong Han Kim and Arthur A. Santilli pp 1227 - 1228; DOI: 10.1021/jm00312a029 |
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O-Demethyldecarbamoylnovobiocin E. J. Hessler and H. K. Jahnke pp 1228 - 1229; DOI: 10.1021/jm00312a030 |
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Synthesis of 5'-substituted derivatives of inosine Alexander Hampton, Monika Bayer, V. S. Gupta, and Samuel Y. Chu pp 1229 - 1232; DOI: 10.1021/jm00312a031 |
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Acylations of some 2-amino-6-halo- and 2-amino-6-alkylthiopurines Elizabeth Dyer and Carl E. Minnier pp 1232 - 1234; DOI: 10.1021/jm00312a032 |
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The hepatocarcinogenicity of some disubstituted 4-dimethylaminoazobenzenes Ellis V. Brown pp 1234 - 1235; DOI: 10.1021/jm00312a033 |
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Derivatives of fluorene. XXVII. New thiofluorenes related to metabolism of the carcinogen N-2-fluorenylacetamide. 2 Moses J. Namkung and T. Lloyd Fletcher pp 1235 - 1236; DOI: 10.1021/jm00312a034 |
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Derivatives of fluorene. XXVIII. New thiofluorenes related to metabolism of the carcinogen N-2-fluorenylacetamide. 3 Hsi-Lung Pan, Moses J. Namkung, and T. Lloyd Fletcher pp 1236 - 1237; DOI: 10.1021/jm00312a035 |
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2,4-Bis (aryloxy)pyrimidines as antimicrobial agents Dolly Ghosh and Mina Mukherjee pp 1237 - 1238; DOI: 10.1021/jm00312a036 |
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Folic acid analogs. I. p-[[(2,4-Diamino-5-pyrimidinyl)methyl]amino]benzoyl-L-glutamic acid and related compounds Louis T. Weinstock, Darrell E. O'Brien, and C. C. Cheng pp 1238 - 1241; DOI: 10.1021/jm00312a037 |
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Effect of monoiodotyrosine metabolites on tyrosine hydroxylase Barry N. Lutsky and Nicolas Zenker pp 1241 - 1242; DOI: 10.1021/jm00312a038 |
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Fluorinated α,α-dialkylphenethylamines Ernst D. Bergmann and Zeev Goldschmidt pp 1242 - 1244; DOI: 10.1021/jm00312a039 |
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Phenothiazines Exhibiting Lesser Extraparamidal Manifestations H. L. Sharma, S. P. Banerjee, V. N .Sharma, and R. L. Mital pp 1244 - 1245; DOI: 10.1021/jm00312a600 |
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Sedative Antiadrenergic, and Hypotensive 2-Substituted 2H-1,2,4-Benzothiadiazin-3(4H)-one 1,1-dioxides S. Hayao, W. G. Stryker, B. M. Phillips, H. Fujimori, and H. Vidrio pp 1246 - 1248; DOI: 10.1021/jm00312a601 |
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7-Trifluoromethoxy and 7-Trifluoromethythio Derivatives of 1,4-Benzodiazepines Francis J. McEvoy, E. N. Greenblatt, A. C .Osterberg, and George R. Allen, Jr. pp 1248 - 1250; DOI: 10.1021/jm00312a602 |
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Sulfonylureas Having Diuretic Activity Bernard Voev, and Kenneth M. Shader pp 1250 - 1251; DOI: 10.1021/jm00312a603 |
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Central Nervous System Depressants. VIII. Pyroles. Robert Bruce Moffett pp 1251 - 1252; DOI: 10.1021/jm00312a604 |
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Some Analogs of 1-p-Chlorobenzyl-5-methylindole-3-acetic Acid. Edward Walton, Susan R. Jenkins, Ruth F. Nutt, and Frederick W. Holly pp 1252 - 1255; DOI: 10.1021/jm00312a605 |
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Synthesis and Biological Activity of Some 3-Substituted Amino-1--carbomoyl- and -thiocarbamoylpyrrolidines William J. Welstead, Jr., Grover C. Helsley, Carl D. Lunsford, Ying-Ho Chen, and P. DaVanzo pp 1255 - 1256; DOI: 10.1021/jm00312a606 |
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S-2-Aminoethyl-S'-ω-Carboxyalkyl Dithiocarbonate Hydrochlonides as Potential Antiradiation Agents Thomas P. Johnston, Carl R. Stringfellow, Jr., and James R. Piper pp 1256 - 1258; DOI: 10.1021/jm00312a607 |
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Synthesis and Antifertility Activity of 4-and5-(ω-Arylalkyl)oxazolidinethiones Daniel Lednicer, and P. Edward Emmert pp 1258 - 1262; DOI: 10.1021/jm00312a608 |
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Synthesis and Pharmacology of p-Methoxycinnamie Acid Derivatives Eun Bang Lee, Kuk Hyun Shin, and Won Sick Woo pp 1262 - 1263; DOI: 10.1021/jm00312a609 |
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4-(4-Pyrimidinyl)pyridinium Salts. Analogs of the Hypoglycemic 4-Pyrazolylpyridinium Salts Victor J. Bauer, Harry P. Palalian, and S. R. Safir pp 1263 - 1264; DOI: 10.1021/jm00312a610 |
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1-Imidazolyl-Derivatives of 2-Hydroxy-3-phenoxypropane V. Sunjic, D. Kolbah, F. Kajfez, and N. Blazevic pp 1264 - 1265; DOI: 10.1021/jm00312a611 |
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Topical Mosquito Repellents. II. Repellent Potency and Duration in Ring-Substituted N,N-Dialkyl- and -Aminoalkylbenzamides. H. L. Johnson, W. A. Skinner, D. Skidmore, and H. I. Maibach pp 1265 - 1268; DOI: 10.1021/jm00312a612 |
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New Compounds - Synthesis of N-Aryl-N'-2-thiazolylguanidines Wahid U. Malik, P. K. Srivastava, and S.C. Merra pp 1268 - 1269; DOI: 10.1021/jm00312a613 |
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New Compounds - Polyiodo Derivatives of Anisidine Isomers Francis B. Alvey, and Charles H. Jarboe pp 1269 - 1269; DOI: 10.1021/jm00312a614 |
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New Compounds - Some Sulfonamide Derivatives of Cyclohexane Yoshio Urno, Shoji Takemura, Kenji Ozawa, and Shigeo Komatsu pp 1269 - 1270; DOI: 10.1021/jm00312a615 |
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New Compounds - Studies in Cinnoline Chemistry. I. The Synthesis of Substituted Phenyl Cinnolyl Sulfides. S. M. Yarnal, and V. V. Badiger pp 1270 - 1270; DOI: 10.1021/jm00312a616 |
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New Compounds - N,N,N'N'-Tetraalkylhomopiperazinium Salts. William F. Hart, and Kenneth E. Jones pp 1270 - 1271; DOI: 10.1021/jm00312a617 |
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Book Reviews pp 1271 - 1271; DOI: 10.1021/jm00312a618 |
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Additions and Corrections - Synthesis and Herbicidal Activity of 1,1-Dimethyl-and 2-Methyl-4-phenylsemicarbazides. Merrill Wilcox pp 1272 - 1272; DOI: 10.1021/jm00312a619 |
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Additions and Corrections - Methoxy Derivatives of 5,5-Diphenylhydantoin and 5-Phenyl-5-benzylhydantoin. Armando Novelli, and Alberto M. De Santis pp 1272 - 1272; DOI: 10.1021/jm00312a620 |
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Additions and Corrections - Synthesis of 3,5-Bishydroxymethyl-6-methyl-2-pyridone, an Isomer of Pyridoxine. Brian Jaques, and John W. Hubbard pp 1272 - 1272; DOI: 10.1021/jm00312a621 |
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Additions and Corrections - Anti-inflammatory 2-Aryl-1,3-indandiones. Joseph G. Lombardino, and Edward H. Wiseman pp 1272 - 1272; DOI: 10.1021/jm00312a622 |
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Additions and Corrections - Cholinesterase Hydrolysis and Substrate Inhibition of Lactoylcholines B. V. Rama Sastry, and Eve C. White pp 1272 - 1272; DOI: 10.1021/jm00312a623 |
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Additions and Corrections - 4-Amino-1-(β-D-ribofuranosyl)benzimidazole. Susan R. Jenkins, Frederick W. Holly, and Roland K. Robins pp 1272 - 1272; DOI: 10.1021/jm00312a624 |